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The Alzheimer?s Unit

Started by IYT, September 21, 2006, 09:12:02 AM

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lumbilly

I've got an extra tea cup Cookie. But it may look funny with your soup mug on the other one.  :eek: Or did we have soup for supper yesterday & tea at brunch? Anybody seen my teeth?  :biggrin:

IYT

If my teeth were the only parts of me I couldn't see, I'd be happy. :-[
"Goatboy's personal favorite, the peach under pear imagery which Monet used to such good affect in his blue ball period . C'mer my little fruit basket "-Bill Hicks

Cookie Parker

Quote from: lumbilly on September 22, 2006, 09:59:02 AM
I've got an extra tea cup Cookie. But it may look funny with your soup mug on the other one.  :eek: Or did we have soup for supper yesterday & tea at brunch? Anybody seen my teeth?  :biggrin:

Thanks, tea cup won't fix...but it would make a nice tassle!!!!

Hey, look at THAT wall!!!

Hey, look...your teeth are here, under the soup cup....YUCK!!!!
Alan Cohen:

    It takes a lot of courage to release the familiar and seemingly secure, to embrace the new. But there is no real security in what is no longer meaningful. There is more security in the adventurous and exciting, for in movement there is life, and in change there is power.

Red Haired Girl

Look at what??? I can't find my glasses...

now, i DID wear glasses didn't I/???? :think:
Magistrate's Wife and Best Friend.

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Sandy Eggo

QuoteMarijuana may help stave off Alzheimer?s
Active ingredient in pot may help preserve brain function
Reuters

Updated: 10:09 a.m. PT Oct 6, 2006

WASHINGTON - Good news for aging hippies: smoking pot may stave off Alzheimer?s disease.

New research shows that the active ingredient in marijuana may prevent the progression of the disease by preserving levels of an important neurotransmitter that allows the brain to function.

Researchers at the Scripps Research Institute in California found that marijuana?s active ingredient, delta-9-tetrahydrocannabinol, or THC, can prevent the neurotransmitter acetylcholine from breaking down more effectively than commercially marketed drugs.

THC is also more effective at blocking clumps of protein that can inhibit memory and cognition in Alzheimer?s patients, the researchers reported in the journal Molecular Pharmaceutics.

The researchers said their discovery could lead to more effective drug treatment for Alzheimer?s, the leading cause of dementia among the elderly.

Those afflicted with Alzheimer?s suffer from memory loss, impaired decision-making, and diminished language and movement skills. The ultimate cause of the disease is unknown, though it is believed to be hereditary.

Marijuana is used to relieve glaucoma and can help reduce side effects from cancer and AIDS treatment.


http://msnbc.msn.com/id/15145917/wid/11915773?GT1=8618
Only after the last tree has been cut down. Only after the last river has been poisoned. Only after the last fish has been caught. Only then will you find that money cannot be eaten. - -Cree Indian Prophecy

"Women who strive to be equal to men lack ambitition" -- anonymous

~Daisy~

From www.webmd.com

Feb. 23, 2005 -- New clues about Alzheimer's disease have emerged from a Spanish study of marijuana. The drug's active ingredients -- cannabinoids -- help prevent brain problems seen in Alzheimer's, say the scientists.

There is no cure for Alzheimer's disease, which progressively damages brain areas involved in memory, judgment, language, and behavior. Alzheimer's disease is the most common form of mental decline, or dementia, in older adults.

The new study didn't test cannabinoids on people living with Alzheimer's disease. Instead, the researchers focused on human brain tissue samples and conducted cannabinoid experiments on rats.

The findings showed that "cannabinoids work both to prevent inflammation and to protect the brain," says researcher Maria de Ceballos in a news release. That "may set the stage for [cannabinoids'] use as a therapeutic approach for [Alzheimer's disease]."

A staff member at Madrid's Cajal Institute, de Ceballos conducted the study with colleagues from nearby Complutense University. Their results appear in the Feb. 23 edition of The Journal of Neuroscience.

The researchers studied human brain tissue samples, some of which were from deceased Alzheimer's patients and some from normal brain tissue.

The typical features seen in the brain tissue of Alzheimer's disease are called plaques. Plaques are protein clumps that are seen outside brain cells, and they have been shown to activate inflammation seen in brain tissue of Alzheimer's disease patients.

Besides the typical plaques seen with Alzheimer's disease, the brain tissues taken from Alzheimer's patients also had many fewer cannabinoid receptors.

Significant changes in the location, expression, and function of cannabinoid receptors may play a role in Alzheimer's disease, write the researchers.

That could mean that the patients had lost the capacity to experience cannabinoids' protective effects, says the news release.

Marijuana and Alzheimer's Mental Decline

The researchers also injected rats with a protein called beta-amyloid, which gave the rats an Alzheimer's-like brain condition.

Some of the same rats were also injected with a cannabinoid. For comparison, other rats got injections of an unrelated protein along with beta-amyloid.

After two months, the rats were tested for learning, memory, and mental functions. The researchers tried to train them to find a platform in a tank of water. The rats had two minutes to find the platform. If they failed, the researchers briefly put the rats on the platform. Four times a day for five days, the rats practiced.

By the fifth day, the rats that received the cannabinoid injections were able to find the platform on their own. Those that didn't get the cannabinoid injections didn't learn to find the platform.

Another interesting result also surfaced. The cannabinoids completely prevented activation of cells that trigger inflammation. These cells gather near plaque and are believed to be involved in the development of Alzheimer's disease.

"Our results indicate that cannabinoid receptors are important in the pathology of Alzheimer's disease and that cannabinoids succeed in preventing the neurodegenerative process occurring in the disease," write the researchers in the journal.

They plan to focus future studies on a cannabinoid receptor that's unrelated to marijuana's "high," says the news release.
If you don't like what you're doing, you can always pick up your needle and move to another groove.
--Timothy Leary

~Daisy~

If you don't like what you're doing, you can always pick up your needle and move to another groove.
--Timothy Leary

Cookie Parker

Quote from: IYT IYT IYT on September 22, 2006, 10:02:10 AM
If my teeth were the only parts of me I couldn't see, I'd be happy. :-[

Wow......read that thing three times really fast..... :confused:
Alan Cohen:

    It takes a lot of courage to release the familiar and seemingly secure, to embrace the new. But there is no real security in what is no longer meaningful. There is more security in the adventurous and exciting, for in movement there is life, and in change there is power.

Red Haired Girl

intersting article on the pot vs Alzheimer's disease ....

sounds like someone is looking for a good excuse for recreational drugs, huh?

I know that smnoking pot is also supposed to be good for glaucoma, as it supposedly reduces the pressure in the eyeball....

puff on, Daisy! LOL

Magistrate's Wife and Best Friend.

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Gryphon

Quote from: Red-Haired Girl on October 08, 2006, 08:27:34 PM
intersting article on the pot vs Alzheimer's disease ....

sounds like someone is looking for a good excuse for recreational drugs, huh?

I know that smnoking pot is also supposed to be good for glaucoma, as it supposedly reduces the pressure in the eyeball....

puff on, Daisy! LOL



LOL! Could marijuana be the fountain of youth?? LOL

Red Haired Girl

If it wasn't, but you tried it anyway, would you care? LOL
Magistrate's Wife and Best Friend.

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Gryphon

Im ashamed to admit that I have! It didnt do a thing but make me sick...Im quite certain that, for me, it would not have any healthful benefits!

Red Haired Girl

have always been a t-totaller myself... and don't think that i have missed anything.
Magistrate's Wife and Best Friend.

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Cookie Parker

Quote from: Red-Haired Girl on October 08, 2006, 08:27:34 PM
intersting article on the pot vs Alzheimer's disease ....

sounds like someone is looking for a good excuse for recreational drugs, huh?

I know that smnoking pot is also supposed to be good for glaucoma, as it supposedly reduces the pressure in the eyeball....

puff on, Daisy! LOL



Actually, it also creates appetites in cancer patients going through chemo which keeps their immune system up and running well or better than without it.  When Clinton removed it from the medicinal list of what the government pays for and allowed the Drug companies to insert marinol at a much higher rate, there has shown to have been a drop in the appetites for these patients.  The chemical is not doing the same job the plant was doing and many people become too sick to take their treatments so the disease progresses much quicker....it's not recreational....totally... :biggrin:
Alan Cohen:

    It takes a lot of courage to release the familiar and seemingly secure, to embrace the new. But there is no real security in what is no longer meaningful. There is more security in the adventurous and exciting, for in movement there is life, and in change there is power.

Red Haired Girl

hmmmm... thanks Cookie.... we learn something new every day....

do you think that it will ever be reintroduced to the medical list of approved meds?
Magistrate's Wife and Best Friend.

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